diff --git a/unified-runtime/test/conformance/exp_command_buffer/commands.cpp b/unified-runtime/test/conformance/exp_command_buffer/commands.cpp
index c49bae2814284..85b0ba0a71431 100644
--- a/unified-runtime/test/conformance/exp_command_buffer/commands.cpp
+++ b/unified-runtime/test/conformance/exp_command_buffer/commands.cpp
@@ -56,12 +56,18 @@ struct urCommandBufferCommandsTest
 UUR_INSTANTIATE_DEVICE_TEST_SUITE(urCommandBufferCommandsTest);
 
 TEST_P(urCommandBufferCommandsTest, urCommandBufferAppendUSMMemcpyExp) {
+  // No USM memcpy command in cl_khr_command_buffer
+  UUR_KNOWN_FAILURE_ON(uur::OpenCL{});
+
   ASSERT_SUCCESS(urCommandBufferAppendUSMMemcpyExp(
       cmd_buf_handle, device_ptrs[0], device_ptrs[1], allocation_size, 0,
       nullptr, 0, nullptr, nullptr, nullptr, nullptr));
 }
 
 TEST_P(urCommandBufferCommandsTest, urCommandBufferAppendUSMFillExp) {
+  // No USM fill command in cl_khr_command_buffer
+  UUR_KNOWN_FAILURE_ON(uur::OpenCL{});
+
   uint32_t pattern = 42;
   ASSERT_SUCCESS(urCommandBufferAppendUSMFillExp(
       cmd_buf_handle, device_ptrs[0], &pattern, sizeof(pattern),
@@ -83,6 +89,10 @@ TEST_P(urCommandBufferCommandsTest, urCommandBufferAppendMemBufferCopyRectExp) {
 }
 
 TEST_P(urCommandBufferCommandsTest, urCommandBufferAppendMemBufferReadExp) {
+  // No buffer read command in cl_khr_command_buffer
+  // See https://github.com/KhronosGroup/OpenCL-Docs/issues/1281
+  UUR_KNOWN_FAILURE_ON(uur::OpenCL{});
+
   std::array<uint32_t, elements> host_data{};
   ASSERT_SUCCESS(urCommandBufferAppendMemBufferReadExp(
       cmd_buf_handle, buffers[0], 0, allocation_size, host_data.data(), 0,
@@ -90,6 +100,10 @@ TEST_P(urCommandBufferCommandsTest, urCommandBufferAppendMemBufferReadExp) {
 }
 
 TEST_P(urCommandBufferCommandsTest, urCommandBufferAppendMemBufferReadRectExp) {
+  // No buffer read command in cl_khr_command_buffer
+  // See https://github.com/KhronosGroup/OpenCL-Docs/issues/1281
+  UUR_KNOWN_FAILURE_ON(uur::OpenCL{});
+
   std::array<uint32_t, elements> host_data{};
   ur_rect_offset_t origin{0, 0, 0};
   ur_rect_region_t region{4, 4, 1};
@@ -99,6 +113,10 @@ TEST_P(urCommandBufferCommandsTest, urCommandBufferAppendMemBufferReadRectExp) {
 }
 
 TEST_P(urCommandBufferCommandsTest, urCommandBufferAppendMemBufferWriteExp) {
+  // No buffer write command in cl_khr_command_buffer
+  // See https://github.com/KhronosGroup/OpenCL-Docs/issues/1281
+  UUR_KNOWN_FAILURE_ON(uur::OpenCL{});
+
   std::array<uint32_t, elements> host_data{};
   ASSERT_SUCCESS(urCommandBufferAppendMemBufferWriteExp(
       cmd_buf_handle, buffers[0], 0, allocation_size, host_data.data(), 0,
@@ -107,6 +125,10 @@ TEST_P(urCommandBufferCommandsTest, urCommandBufferAppendMemBufferWriteExp) {
 
 TEST_P(urCommandBufferCommandsTest,
        urCommandBufferAppendMemBufferWriteRectExp) {
+  // No buffer write command in cl_khr_command_buffer
+  // See https://github.com/KhronosGroup/OpenCL-Docs/issues/1281
+  UUR_KNOWN_FAILURE_ON(uur::OpenCL{});
+
   std::array<uint32_t, elements> host_data{};
   ur_rect_offset_t origin{0, 0, 0};
   ur_rect_region_t region{4, 4, 1};
@@ -123,12 +145,18 @@ TEST_P(urCommandBufferCommandsTest, urCommandBufferAppendMemBufferFillExp) {
 }
 
 TEST_P(urCommandBufferCommandsTest, urCommandBufferAppendUSMPrefetchExp) {
+  // No Prefetch command in cl_khr_command_buffer
+  UUR_KNOWN_FAILURE_ON(uur::OpenCL{});
+
   ASSERT_SUCCESS(urCommandBufferAppendUSMPrefetchExp(
       cmd_buf_handle, device_ptrs[0], allocation_size, 0, 0, nullptr, 0,
       nullptr, nullptr, nullptr, nullptr));
 }
 
 TEST_P(urCommandBufferCommandsTest, urCommandBufferAppendUSMAdviseExp) {
+  // No advise command in cl_khr_command_buffer
+  UUR_KNOWN_FAILURE_ON(uur::OpenCL{});
+
   ASSERT_SUCCESS(urCommandBufferAppendUSMAdviseExp(
       cmd_buf_handle, device_ptrs[0], allocation_size, 0, 0, nullptr, 0,
       nullptr, nullptr, nullptr, nullptr));
diff --git a/unified-runtime/test/conformance/exp_command_buffer/fill.cpp b/unified-runtime/test/conformance/exp_command_buffer/fill.cpp
index 494c2b26c4ba4..1b22a9bba5727 100644
--- a/unified-runtime/test/conformance/exp_command_buffer/fill.cpp
+++ b/unified-runtime/test/conformance/exp_command_buffer/fill.cpp
@@ -109,6 +109,9 @@ UUR_DEVICE_TEST_SUITE_WITH_PARAM(
     printFillTestString<urCommandBufferFillCommandsTest>);
 
 TEST_P(urCommandBufferFillCommandsTest, Buffer) {
+  // No buffer read command in cl_khr_command_buffer
+  UUR_KNOWN_FAILURE_ON(uur::OpenCL{});
+
   ASSERT_SUCCESS(urCommandBufferAppendMemBufferFillExp(
       cmd_buf_handle, buffer, pattern.data(), pattern_size, 0, size, 0, nullptr,
       0, nullptr, &sync_point, nullptr, nullptr));
@@ -128,6 +131,9 @@ TEST_P(urCommandBufferFillCommandsTest, Buffer) {
 }
 
 TEST_P(urCommandBufferFillCommandsTest, ExecuteTwice) {
+  // No buffer read command in cl_khr_command_buffer
+  UUR_KNOWN_FAILURE_ON(uur::OpenCL{});
+
   ASSERT_SUCCESS(urCommandBufferAppendMemBufferFillExp(
       cmd_buf_handle, buffer, pattern.data(), pattern_size, 0, size, 0, nullptr,
       0, nullptr, &sync_point, nullptr, nullptr));
@@ -149,6 +155,9 @@ TEST_P(urCommandBufferFillCommandsTest, ExecuteTwice) {
 }
 
 TEST_P(urCommandBufferFillCommandsTest, USM) {
+  // No USM fill command in cl_khr_command_buffer
+  UUR_KNOWN_FAILURE_ON(uur::OpenCL{});
+
   ASSERT_SUCCESS(urCommandBufferAppendUSMFillExp(
       cmd_buf_handle, device_ptr, pattern.data(), pattern_size, size, 0,
       nullptr, 0, nullptr, &sync_point, nullptr, nullptr));